How to Read Certificates of Analysis (COAs)

A COA (Certificate of Analysis) is your proof that a peptide has been tested by a third-party laboratory. Learning to read these documents is essential for any serious researcher. 1. Product Identification - Peptide name and molecular formula - Batch/Lot number (must match your vial) - Date of analysis - Laboratory name and accreditation 2. Purity Analysis (HPLC) - Target: 98%+ for most peptides - Method: High-Performance Liquid Chromatography - Look for the main peak percentage 3. Mass Spectrometry (MS) - Confirms molecular identity - Expected vs. observed molecular weight - Should match within 0.5 daltons 4. Additional Tests - Endotoxin levels (bacterial contamination) - Amino acid sequencing - Appearance and solubility - No batch number or mismatched batch - Generic or recycled COAs - Missing laboratory information - Purity below 95% - Outdated testing (6+ months old) At Revive Research, every vial includes a QR code that links directly to its batch-specific COA. This en