> Educational Content Only: This compound is discussed for educational purposes only and is not currently offered by our company. PT-141, also known as Bremelanotide, is a synthetic peptide analog of alpha-melanocyte-stimulating hormone (α-MSH). Originally developed from the tanning peptide Melanotan II, PT-141 has become a subject of significant research interest due to its unique mechanism of action through the central nervous system rather than the vascular system. PT-141 is a cyclic heptapeptide with the sequence Ac-Nle-cycloAsp-His-D-Phe-Arg-Trp-Lys-OH. Key characteristics include: - Molecular Weight: 1,025 Da - Water solubility: Good - Stability: Requires refrigeration - Half-life: Approximately 2-4 hours PT-141 exerts its effects primarily through melanocortin receptors, particularly MC3R and MC4R in the central nervous system. - MC4R Agonism: Primary target in the hypothalamus, involved in sexual response pathways - MC3R Interaction: Secondary binding site with poten
PT-141 (Bremelanotide): Melanocortin System Research Guide
Comprehensive overview of PT-141/Bremelanotide, a melanocortin receptor agonist, including its mechanism of action, research applications in sexual function studies, and key scientific findings.