TB-500 is a synthetic version of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino acid peptide found in virtually all human and animal cells (except red blood cells). It represents one of the most researched regenerative peptides. Molecular Weight: 4,963 Da (4.9 kDa) The relatively low molecular weight allows for excellent tissue penetration throughout the body. TB-500 is the main actin-sequestering peptide in mammalian cells: - Binds to G-actin (monomeric form) - Prevents uncontrolled polymerization - Promotes cell migration by regulating cytoskeleton dynamics - Enables keratinocytes, fibroblasts, and endothelial cells to migrate to injury sites Research demonstrates: - Stimulation of endothelial cell proliferation and migration - Promotion of new capillary formation in wound beds - Enhanced tissue oxygenation and nutrient delivery - 4-6× upregulation during early blood vessel formation - Stem cell mobilization and recruitment to damaged tissue - Enhanced keratinocyte
TB-500: Thymosin Beta-4 Research Guide
A detailed look at TB-500, the synthetic version of Thymosin Beta-4 studied for tissue repair and regeneration.