> Educational Content Only: This compound is discussed for educational purposes only and is not currently offered by our company. Thymosin Alpha-1 (Tα1) is a 28-amino acid peptide originally isolated from thymic tissue. First characterized by Dr. Allan Goldstein in the 1970s, this naturally occurring peptide plays a crucial role in T-cell development and immune system regulation. It has become an important research tool for studying immune modulation mechanisms. - Molecular Weight: 3,108 Da - Amino Acid Sequence: Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN-OH - Isoelectric Point: 4.2 (acidic peptide) - Solubility: Water-soluble - N-terminal: Acetylated serine Thymosin Alpha-1 exerts immunomodulatory effects through multiple pathways: - TLR Signaling: Activates Toll-like receptor 9 (TLR9) on dendritic cells - T-Cell Maturation: Promotes differentiation of T-cell precursors - Cytokine Modulation: Influences IL-2, IFN-α, and IFN-γ production - NK Cell Activation: Enhances natural killer ce
Thymosin Alpha-1: Immune Modulation Research Guide
Explore Thymosin Alpha-1, a thymic peptide with immunomodulatory properties. Learn about its mechanism of action, research applications in immune function studies, and key scientific findings.